Electrostatic repulsion as an additional selectivity factor in asymmetric proline catalysis.
نویسندگان
چکیده
The metal free, single amino acid-catalyzed asymmetric desymmetrization (ADS) of meso-compounds with nitrosobenzene has been investigated using DFT. In this communication, we describe the role of electrostatic and dipole-dipole interactions in amino acid-catalyzed reactions, which has not previously been invoked in discussions of these important reactions.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 4 14 شماره
صفحات -
تاریخ انتشار 2006